• Sensitization Prevalence for Benzalkonium Chloride and ...

    Benzalkonium chloride (BAK) is a widely used quaternary ammonium cationic detergent. It has occasionally been reported as a cause of allergic dermatitis. The agent is the most commonly used...

  • Strong irritants masquerading as skin allergens: the case of ...

    /pubmed/151863751. Contact Dermatitis. 2004 Apr;50(4):213-7. Strong irritants masquerading as skin allergens: the case of benzalkonium chloride. Basketter DA(1), Marriott M, Gilmour NJ, White IR. Author information: (1)Safety and Environmental Assurance Centre, Unilever Colworth Laboratory, Sharnbrook, Bedford, UK. [email protected] Author: David A. Basketter, Marie Marriott, Nicola J. Gilmour, Ian R. WhiteCited by: 104Publish Year: 2004

  • Benzalkonium Chloride: A Skin Irritant and Sensitizer in ...

    CachedOct 05, 2017 · Products that contain benzalkonium chloride (BAK), a commonly used preservative in various personal care products, ophthalmic solutions, nasal sprays, and cleaning agents, should be used with caution in people with compromised skin barriers, according to a recent study published in Dermatitis. Author: Sheila Jacobs

  • Patch Test of Benzalkonium Chloride Disinfectant Spray - Full ...

    clinicaltrials.gov/ct2/show/NCT01762982 CachedBenzalkonium chloride is recognized as safe and effective for short term use as first aid antiseptic drug products. In this study, benzalkonium chloride disinfectant spray will be compared to a positive control, and two negative control for irritancy potential on normal skin according to Chinese Patch Test Guideline (China Health Authority 2002).

  • Benzalkonium chloride contact dermatitis | DermNet NZ

    /topics/benzalkonium-chloride... CachedWhat is benzalkonium chloride contact dermatitis? When benzalkonium chloride comes into contact with the skin, it can cause irritant contact dermatitis or allergic contact dermatitis in some individuals. Benzalkonium chloride is a well-known irritant [1]. Irritant contact dermatitis to benzalkonium chloride is more common than allergic contact dermatitis. Contact allergy to preservatives | DermNet NZ

  • Effect of the Hand Antiseptic Agents Benzalkonium Chloride ...

    CachedEffect of the Hand Antiseptic Agents Benzalkonium Chloride, Povidone-Iodine, Ethanol, and Chlorhexidine Gluconate on Atopic Dermatitis in NC/Nga Mice Kaori Sadakane, Takamichi Ichinose Department of Health Sciences, Oita University of Nursing and Health Sciences, 2944-9 Megusuno, Oita City, Oita 870-1201, Japan

  • Benzalkonium Chloride Update | The Dermatologist

    benzalkonium... CachedNov 11, 2017 · Benzalkonium Chloride Update. This article discusses benzalkonium chloride, within the context of its historical and clinical significance in association with its use in antiseptics, cosmetics, detergents, and topical medications. Allergic contact dermatitis (ACD) is a socially and economically significant condition.

  • 2 Final Report on the Safety Assessment of Benzalkonium Chloride

    journals.sagepub.com/doi/10.3109/10915818909010524Benzalkonium Chloride is a mixture of alkylbenzyldimethylammonium chlorides. The ingredient is used in cosmetic products as a foaming cleansing and bactericidal agent at concentrations up to 5.0%. The compound was nonmuta-genic in several different cell assays.

  • 2 Final Report on the Safety Assessment of Benzalkonium Chloride

    journals.sagepub.com/doi/pdf/10.3109/...Final Report on the Safety Assessment of Benzalkonium Chloride Benzalkonium Chloride is a mixture of alkylbenzyldimethylammonium chlo- rides. The ingredient is used in cosmetic products as a foaming cleansing and bactericidal agent at concentrations up to 5.0%. The compound was nonmuta- genic in several different cell assays.

  • Benzalkonium Chloride: A Known Irritant and Novel Allergen ...

    journals.lww.com/dermatitis/Abstract/2016/01000/... CachedBenzalkonium chloride (BAK), a detergent and preservative found in health care and household products, is an established irritant, yet BAK is seldom considered to cause allergic contact dermatitis. We have, however, observed positive patch test reactions more often than is typically reported.

  • Benzalkonium Chloride | allergEAZE Contact Dermatitis Allergens

    CachedBenzalkonium Chloride | allergEAZE Contact Dermatitis Allergens The allergEAZE epicutaneous contact allergen product line consists of over 600 individual allergens. Information sheets include description, where allergen is found & how to avoid contact.

  • Benzalkonium Chloride - an overview | ScienceDirect Topics

    benzalkonium-chlorideBenzalkonium chloride is a quaternary ammonium compound and it is the most commonly used antimicrobial preservative. It was initially used in hard contact lens solutions but is now ubiquitous. Currently, it can be found in most topical multi-use ophthalmic preparations.6. BAK is a detergent that denatures proteins and causes lysis of ...

  • Allergic contact dermatitis to dorzolamide and benzalkonium ...

    contact-dermatitis-to... CachedA few cases of true allergic contact dermatitis to Dorzolamide have been reported [5, 6] but, to our knowledge, this is the first report of an allergy to both the active drug and the excipient. Moreover, contact sensitization to benzalkonium chloride alone is rare [7]. Author: Diego Orsini, Andrea D'Arino, Flavia Pigliacelli, Chiara Assorgi, Alessandra Latini, Antonio Cristau...Publish Year: 2018

  • Allergic contact dermatitis to dorzolamide and benzalkonium ...

    /pmc/articles/PMC6232551A few cases of true allergic contact dermatitis to Dorzolamide have been reported [5, 6] but, to our knowledge, this is the first report of an allergy to both the active drug and the excipient. Moreover, contact sensitization to benzalkonium chloride alone is rare [ 7 ]. Author: Diego Orsini, Andrea D'Arino, Flavia Pigliacelli, Chiara Assorgi, Alessandra Latini, Antonio Cristau...Publish Year: 2018

  • Flexural allergic contact dermatitis to benzalkonium chloride ...

    Benzalkonium chloride (BAK) is an acknowledged irritant but has also been identified as a cause of allergic contact dermatitis. The antiseptic bath emollient Oilatum Plus (Stiefel, High Wycombe,...

  • Benzalkonium chloride - Wikipedia

    en.wikipedia.org/wiki/Alkyldimethylbenzyl... Cached[citation needed] However, prolonged or repeated skin contact may cause dermatitis. Medicine. Benzalkonium chloride is a frequently used preservative in eye drops; typical concentrations range from 0.004% to 0.01%. Stronger concentrations can be caustic and cause irreversible damage to the corneal endothelium. Chemical formula: variableMolar mass: variableEC Number: 264-151-6RTECS number: BO3150000

  • Irritant Contact Dermatitis Clinical Presentation: History ...

    emedicine.medscape.com/article/1049353-clinical CachedAug 21, 2019 · Acute delayed irritant contact dermatitis is characteristic of certain irritants, such as benzalkonium chloride (eg, zephiran, a preservative and disinfectant), which elicits a deferred (8-24 h...

  • Benzalkonium chloride: A known irritant and novel allergen ...

    mayoclinic.pure.elsevier.com/en/publications/... CachedBackground Benzalkonium chloride (BAK), a detergent and preservative found in health care and household products, is an established irritant, yet BAK is seldom considered to cause allergic contact dermatitis. We have, however, observed positive patch test reactions more often than is typically reported. Author: Ashley B. Wentworth, James A. Yiannias, Mark D.P. Davis, Jill M. KillianCited by: 14Publish Year: 2016

  • Is the irritant benzalkonium chloride a contact allergen? A ...

    www.dermatitisacademy.com/wp-content/uploads/...Background: Benzalkonium chloride (BAC) is a well-recognized irritant. However, doubts exist that it is also a contact allergen. Objective: Analysis of clinical patch test data addressing the reaction profile and synchronous repro-ducibility of BAC 0.1% in petrolatum (pet.) and possible increases in risk of BAC contact allergy in

  • Benzalkonium Chloride: Indications, Side Effects, Warnings ...

    /cdi/benzalkonium-chloride.html CachedMedically reviewed by Drugs.com. Last updated on Jan 5, 2020. It is used to prevent skin infections. If you have an allergy to benzalkonium chloride or any other part of benzalkonium chloride. If you are allergic to benzalkonium chloride; any part of benzalkonium chloride; or any other drugs, foods, or substances. Brand names: Neosporin Wound Cleanser, CureChrome, Antimicrobial Cleanser, Merthiolate, HandClens 2 in 1Drug class: Antiseptic and germicides

  • Benzalkonium Chloride Drug Information, Professional

    /mmx/benzalkonium-chloride.html CachedTartrates {02} (benzalkonium chloride may be chemically inactivated by the above agents; contact between benzalkonium chloride spermicides and any product containing the above ingredients should be avoided {02} {21} {104})

  • CDI Allergen Info Sheets Benzalkonium chloride

    www.contactdermatitisinstitute.com/pdfs/allergens...Your patch test result indicates that you have a contact allergy to benzalkonium chloride. This contact allergy may cause your skin to react when it is exposed to this substance although it may take several days for the symptoms to appear. Typical symptoms include redness, swelling, itching, and fluid-filled blisters. File Size: 80KBPage Count: 1

  • Benzalkonium Chloride Contact Dermatitis - Image Results

    More Benzalkonium Chloride Contact Dermatitis images

  • Allergic Contact Sensitivity to Benzalkonium Chloride ...

    jamanetwork.com/journals/jamadermatology/full... CachedBenzalkonium chloride (BAK) is a widely used quaternary ammonium cationic detergent. It has occasionally been reported as a cause of allergic dermatitis. The agent is the most commonly used preservative in ophthalmic medications, solutions for contact lenses, and "artificial tears." Author: Alexander A. Fisher, Michael A. StillmanCited by: 82Publish Year: 1972

  • Hand Hygiene in Preventing COVID-19 Transmission | MDedge ...

    Irritant contact dermatitis (ICD) is most commonly associated with wet work and is frequently seen in health care workers in relation to hand hygiene, with survey-based studies reporting 25% to 55% of nurses affected. 3-5 In a prospective study (N = 102), health care workers who washed their hands more than 10 times per day were55% more likely ...

  • Benzalkonium Chloride - Uses, Side Effects, Information

    b4brands.com/.../benzalkonium-chloride CachedEffects of short-term exposure, Benzethonium chloride is corrosive to the eyes and is irritating to the skin. Long-term effects from repeated exposure may cause dermatitis. Notice

  • [citation needed] However, prolonged or repeated skin contact may cause dermatitis. Medicine. Benzalkonium chloride is a frequently used preservative in eye drops; typical concentrations range from 0.004% to 0.01%. Stronger concentrations can be caustic and cause irreversible damage to the corneal endothelium. Benzalkonium chloride - Wikipedia

    https://en.wikipedia.org/wiki/Alkyldimethylbenzylammonium_chloride

  • Benzalkonium Chlorides: Uses, Regulatory Status, and ...

    aem.asm.org/content/85/13/e00377-19 CachedBenzalkonium chlorides (BACs) are chemicals with widespread applications due to their broad-spectrum antimicrobial properties against bacteria, fungi, and viruses. This review provides an overview of the market for BACs, as well as regulatory measures and available data on safety, toxicity, and environmental contamination. We focus on the effect of frequent exposure of microbial communities to ... Author: Beatriz Merchel Piovesan Pereira, Ilias TagkopoulosCited by: 5Publish Year: 2019

  • Benzalkonium Chloride: An Irritant and Sensitizer : Dermatitis

    journals.lww.com/dermatitis/Abstract/2017/11000/... CachedBackground Benzalkonium chloride (BAK) is a known irritant, and potentially cross-reacting quaternary ammonium compounds are commonly used as preservatives in personal care products. Objective The aim of the study was to review positive reactions to BAK in 615 patients patch tested for suspected allergic contact dermatitis.

  • Benzalkonium Chloride | Allergic Contact Dermatitis Database

    www.contactdermatitisinstitute.com/benzalkonium... CachedBenzalkonium chloride is used to preserve cosmetics, mouthwashes, and skin cleansers, and to sterilize medical and dental instruments. It is also used in agricultural, textile, and metallurgical processes.

  • Strong irritants masquerading as skin allergens: the case of ...

    onlinelibrary.wiley.com/doi/full/10.1111/j.0105...However, on occasions, benzalkonium chloride has been reported as a cause of allergic contact dermatitis (ACD) (1, 4) and has been considered to produce positive responses in some sensitization assays . However, irritant and ACD have a generally very similar appearance in skin, both clinically and experimentally. Author: David A. Basketter, Marie Marriott, Nicola J. Gilmour, Ian R. WhiteCited by: 104Publish Year: 2004

  • People also ask Can benzethonium chloride cause allergy? Your patch test result indicates that you have a contact allergy to benzalkonium chloride. This contact allergy may cause your skin to react when it is exposed to this substance although it may take several days for the symptoms to appear. CDI Allergen Info Sheets Benzalkonium chloride

    Benzalkonium%20chloride.pdfSee all results for this question What is the effect of benzalkonium chloride on mitochondria? Using in vitro research on human corneal epithelial cells, benzalkonium chloride was found to inhibit mitochondrial ATP and oxygen consumption in a concentration-dependent manner. At its pharmaceutical concentrations (107–667 μM), it inhibited mitochondrial function > 90%. Benzalkonium chloride - an overview | ScienceDirect Topics

  • Flexural allergic contact dermatitis to benzalkonium chloride ...

    onlinelibrary.wiley.com/doi/full/10.1111/j.1365...Benzalkonium chloride (BAK) is an acknowledged irritant but has also been identified as a cause of allergic contact dermatitis. The antiseptic bath emollient Oilatum ® Plus (Stiefel, High Wycombe, U.K.) contains a relatively high concentration of 6% BAK. Author: S. Hann, T.M. Hughes, N.M. StoneCited by: 17Publish Year: 2007

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